BDBM50020579 3-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-phenylamine::CHEMBL423045

SMILES Nc1cccc(CCN2CCN(CC2)c2cccc(c2)C(F)(F)F)c1

InChI Key InChIKey=RPESUAWYAQFNSQ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020579   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020579(3-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  4nMAssay Description:Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020579(3-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  5nMAssay Description:Compound was tested in vitro for the inhibition of [3H]-DPAT (1 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020579(3-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  8.10nMAssay Description:Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50020579(3-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  10nMAssay Description:Compound was tested in vitro for the inhibition of [3H]-DPAT (1 nM) binding to 5-HT1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed