BDBM50020850 2-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzoic acid::CHEMBL11146

SMILES Cn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccccc1C(O)=O

InChI Key InChIKey=BBISNWCHHLHHHN-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020850   

TargetAdenosine receptor A1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50020850(CHEMBL11146 | 2-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-te...)
Affinity DataIC50: 2.50E+3nMAssay Description:Binding affinity against bovine brain adenosine A1 receptor by using N6-[3H]- cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50020850(CHEMBL11146 | 2-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-te...)
Affinity DataKi:  1.11E+4nMAssay Description:Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50020850(CHEMBL11146 | 2-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-te...)
Affinity DataKi: >3.00E+4nMAssay Description:Antagonism of cyclic [3H]AMP accumulation elicited by 15 uM 2-chloroadenosine in [3H]adenine-labeled guinea pig cerebral cortical slices at A2 recept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50020850(CHEMBL11146 | 2-(1,3-Dimethyl-2,6-dioxo-2,3,6,7-te...)
Affinity DataKi: >5.00E+4nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed