BDBM50021459 8-(4-Chloro-2-methoxy-phenyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL290643

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(Cl)cc1OC

InChI Key InChIKey=SENICTHRDKBJSR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021459   

TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021459(CHEMBL290643 | 8-(4-Chloro-2-methoxy-phenyl)-1,3-d...)
Affinity DataKi:  420nMAssay Description:Binding affinity against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021459(CHEMBL290643 | 8-(4-Chloro-2-methoxy-phenyl)-1,3-d...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50021459(CHEMBL290643 | 8-(4-Chloro-2-methoxy-phenyl)-1,3-d...)
Affinity DataKi:  6.53E+3nMAssay Description:Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed