BDBM50022280 4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-prop-2-ynyl-amino]-benzoic acid::CHEMBL279732

SMILES Nc1nc2ncc(CN(CC#C)c3ccc(cc3)C(O)=O)nc2c(=O)[nH]1

InChI Key InChIKey=HKTKOVQHDBPQRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022280   

TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022280(4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-prop-2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against dihydrofolate reductase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022280(4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-prop-2-...)
Affinity DataIC50: 2.90E+5nMAssay Description:Inhibitory activity against thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed