BDBM50022553 CHEMBL36075::Propionic acid 1-[4-hydroxy-3-(thiazol-2-ylcarbamoyl)-8-trifluoromethyl-quinolin-2-yl]-propyl ester

SMILES CCC(OC(=O)CC)c1nc2c(cccc2c(O)c1C(=O)Nc1nccs1)C(F)(F)F

InChI Key InChIKey=BSKWKFRABGXDBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50022553   

TargetProstaglandin G/H synthase 1/2(Bovine)
Centre De Recherches Roussel-Uclaf

Curated by ChEMBL
LigandPNGBDBM50022553(Propionic acid 1-[4-hydroxy-3-(thiazol-2-ylcarbamo...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Centre De Recherches Roussel-Uclaf

Curated by ChEMBL
LigandPNGBDBM50022553(Propionic acid 1-[4-hydroxy-3-(thiazol-2-ylcarbamo...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed