BDBM50023058 (1-{1-[1-Cyclohexylmethyl-2-hydroxy-4-(propane-2-sulfonyl)-butylcarbamoyl]-3-methyl-butylcarbamoyl}-2-phenyl-ethyl)-carbamic acid tert-butyl ester::CHEMBL50412

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CCS(=O)(=O)C(C)C

InChI Key InChIKey=JMAABOIQSWCINN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50023058   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023058((1-{1-[1-Cyclohexylmethyl-2-hydroxy-4-(propane-2-s...)
Affinity DataIC50: 14nMAssay Description:Inhibition against purified human renal reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023058((1-{1-[1-Cyclohexylmethyl-2-hydroxy-4-(propane-2-s...)
Affinity DataIC50: 77nMAssay Description:Inhibition against human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023058((1-{1-[1-Cyclohexylmethyl-2-hydroxy-4-(propane-2-s...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition against cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023058((1-{1-[1-Cyclohexylmethyl-2-hydroxy-4-(propane-2-s...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition against rat plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed