BDBM50023070 CHEMBL300724::{1-[1-(1-Cyclohexylmethyl-4-ethanesulfonyl-2-hydroxy-butylcarbamoyl)-2-(3H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CCS(=O)(=O)CC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=FAQKQMALCLBRHM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50023070   

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023070({1-[1-(1-Cyclohexylmethyl-4-ethanesulfonyl-2-hydro...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition against purified human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023070({1-[1-(1-Cyclohexylmethyl-4-ethanesulfonyl-2-hydro...)
Affinity DataIC50: 28nMAssay Description:Inhibition against human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023070({1-[1-(1-Cyclohexylmethyl-4-ethanesulfonyl-2-hydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition against rat plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50023070({1-[1-(1-Cyclohexylmethyl-4-ethanesulfonyl-2-hydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition against cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed