BDBM50023140 6-(2-Fluoro-phenyl)-4-(1H-indol-3-ylmethyl)-1-methyl-4H-2,3,5,10b-tetraaza-benzo[e]azulene(0.5H2O.0.4Et2O)::CHEMBL51569

SMILES Cc1nnc2[C@@H](Cc3c[nH]c4ccccc34)N=C(c3ccccc3F)c3ccccc3-n12

InChI Key InChIKey=VKMJGKFQKLVODR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50023140   

TargetCholecystokinin receptor type A(Rat)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50023140(6-(2-Fluoro-phenyl)-4-(1H-indol-3-ylmethyl)-1-meth...)
Affinity DataIC50: 300nMAssay Description:Displacement of [125I]CCK from Cholecystokinin receptor of rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50023140(6-(2-Fluoro-phenyl)-4-(1H-indol-3-ylmethyl)-1-meth...)
Affinity DataIC50: 1.20E+3nMAssay Description:Half-maximal inhibition of [125I]-CCK-33 binding to rat pancreas cholecystokinin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50023140(6-(2-Fluoro-phenyl)-4-(1H-indol-3-ylmethyl)-1-meth...)
Affinity DataIC50: 1.20E+4nMAssay Description:Half-maximal inhibition of binding of [125I]gastrin to guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50023140(6-(2-Fluoro-phenyl)-4-(1H-indol-3-ylmethyl)-1-meth...)
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of [125I]gastrin from guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50023140(6-(2-Fluoro-phenyl)-4-(1H-indol-3-ylmethyl)-1-meth...)
Affinity DataIC50: 3.90E+4nMAssay Description:Half-maximal inhibition of [125I]CCK-33 binding to guinea pig brain(cortex) cholecystokinin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed