BDBM50023339 CHEMBL3334564

SMILES Fc1ccc(cc1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1

InChI Key InChIKey=ARNKXFZQMPFVOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50023339   

TargetHepatocyte growth factor receptor(Human)
Hutchison Medipharma

Curated by ChEMBL
LigandPNGBDBM50023339(CHEMBL3334564)
Affinity DataIC50: 6nMAssay Description:Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Hutchison Medipharma

Curated by ChEMBL
LigandPNGBDBM50023339(CHEMBL3334564)
Affinity DataIC50: 12nMAssay Description:Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed