BDBM50024135 CHEMBL3325532

SMILES Fc1ccc(cc1)[C@@H]1CNCC[C@H]1COc1cc(F)c(cc1F)S(=O)(=O)Nc1ncns1

InChI Key InChIKey=XSBUZAIFXFCWIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50024135   

TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50024135(CHEMBL3325532)
Affinity DataIC50: 32nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells assessed as reduction in sodium current at -60 mV holding potential by PatchXpress platform based w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50024135(CHEMBL3325532)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells assessed as reduction in sodium current at -60 mV holding potential by PatchXpress platform based w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed