BDBM50024253 CHEMBL3334887

SMILES CCOC(=O)c1ccc(cc1)-c1cn(Cc2ccccc2)c2ccccc12

InChI Key InChIKey=VFHUVLOTZSSZDR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50024253   

TargetProteinase-activated receptor 4(Human)
Northwest Agriculture & Forestry University

Curated by ChEMBL
LigandPNGBDBM50024253(CHEMBL3334887)
Affinity DataIC50: 66nMAssay Description:Antagonist activity at PAR4 in human platelets after 10 mins by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteinase-activated receptor 4(Human)
Northwest Agriculture & Forestry University

Curated by ChEMBL
LigandPNGBDBM50024253(CHEMBL3334887)
Affinity DataIC50: 66nMAssay Description:Antagonist activity at PAR4 in PAR-4-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Northwest Agriculture & Forestry University

Curated by ChEMBL
LigandPNGBDBM50024253(CHEMBL3334887)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at PAR1 in PAR-1-AP-stimulated human platelets compound pretreated for 5 mins by fluorescent PAC1 integrin alpha2bb3 activation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Northwest Agriculture & Forestry University

Curated by ChEMBL
LigandPNGBDBM50024253(CHEMBL3334887)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed