BDBM50024848 CHEMBL3337824

SMILES CC(C)Cn1nc(C)c(c1-c1ccc(F)cc1)-c1ccc2OCC(=O)Nc2c1

InChI Key InChIKey=JGAKOXMSUKTZLQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50024848   

TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50024848(CHEMBL3337824)
Affinity DataIC50: 49nMAssay Description:Antagonist activity at human mineralocorticoid receptor expressed in COS1 cells after 1 day by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50024848(CHEMBL3337824)
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]aldosterone from human mineralocorticoid receptor expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50024848(CHEMBL3337824)
Affinity DataIC50: 390nMAssay Description:Displacement of [3H]-Dexamethasone from glucocorticoid receptor (unknown origin) expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50024848(CHEMBL3337824)
Affinity DataIC50: 3.70E+3nMAssay Description:Displacement of [3H]testosterone from androgen receptor (unknown origin) expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50024848(CHEMBL3337824)
Affinity DataIC50: 4.30E+3nMAssay Description:Displacement of [[3H]-Progesterone from progesterone receptor (unknown origin) expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed