BDBM50025147 2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-2-chloro-benzoylamino}-pentanedioic acid::CHEMBL141546

SMILES Nc1nc2ccc(CN(CC#C)c3ccc(C(=O)NC(CCC(O)=O)C(O)=O)c(Cl)c3)cc2c(=O)[nH]1

InChI Key InChIKey=QNPWCABZSJTCIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025147   

TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50025147(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of L1210 thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50025147(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of L1210 thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50025147(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 1.10E+4nMAssay Description:The compound was evaluated in vitro for inhibition of purified L1210 dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed