BDBM50025150 2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-2-methyl-benzoylamino}-pentanedioic acid::CHEMBL342302

SMILES Cc1cc(ccc1C(=O)NC(CCC(O)=O)C(O)=O)N(CC#C)Cc1ccc2nc(N)[nH]c(=O)c2c1

InChI Key InChIKey=QXYWKDBPARNGDQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025150   

TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50025150(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of L1210 thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50025150(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of L1210 thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50025150(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 2.50E+4nMAssay Description:The compound was evaluated in vitro for inhibition of purified L1210 dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed