BDBM50025974 2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(4,5,6-trihydroxy-2-methyl-tetrahydro-pyran-3-yloxy)-chromen-4-one::CHEMBL171315

SMILES CC1OC(O)C(O)C(O)C1Oc1c(O)c2c(cc(O)cc2=O)oc1-c1ccc(O)c(O)c1

InChI Key InChIKey=QFUJGFKUXJMOFE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50025974   

LigandPNGBDBM50025974(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(4,5,6-tr...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Orange A column at day 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50025974(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(4,5,6-tr...)
Affinity DataIC50:  3.85E+4nMAssay Description:IC50 was measured as concentration required to inhibit 50% of HIV-integrase integrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50025974(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(4,5,6-tr...)
Affinity DataIC50:  6.00E+4nMAssay Description:IC50 was measured as concentration required to inhibit 50% of HIV-integrase cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50025974(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(4,5,6-tr...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50025974(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(4,5,6-tr...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50025974(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(4,5,6-tr...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50025974(2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-(4,5,6-tr...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibitory activity of the compound against human placental aldose reductase in Sepharose 4B column at day 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed