BDBM50026272 2-{4-[(2,4-Diamino-quinazolin-6-ylamino)-methyl]-benzoylamino}-pentanedioic acid::CHEMBL423123

SMILES Nc1nc(N)c2cc(NCc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)ccc2n1

InChI Key InChIKey=SSPKJOYJIAOUSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50026272   

TargetDihydrofolate reductase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50026272(2-{4-[(2,4-Diamino-quinazolin-6-ylamino)-methyl]-b...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of rat liver dihydrofolate reductase assayed spectrophotometrically at 340 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed