BDBM50026728 CHEMBL3331484

SMILES Clc1ccc(CN(C2CC2)C2CNC2)cc1Cl

InChI Key InChIKey=AMGZVHXDDMROJU-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50026728   

TargetSodium-dependent serotonin transporter(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026728(CHEMBL3331484)
Affinity DataIC50: 114nMAssay Description:Inhibition of human SERT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026728(CHEMBL3331484)
Affinity DataIC50: 265nMAssay Description:Inhibition of human DAT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026728(CHEMBL3331484)
Affinity DataIC50: 479nMAssay Description:Inhibition of human NET expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026728(CHEMBL3331484)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant CYP3A4 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026728(CHEMBL3331484)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026728(CHEMBL3331484)
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by automated whole-cell patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026728(CHEMBL3331484)
Affinity DataIC50: 8.08E+3nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026728(CHEMBL3331484)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026728(CHEMBL3331484)
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of human recombinant CYP1A2 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed