BDBM50026730 CHEMBL3331503

SMILES CC(C)N(CC1CNC1)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=IXTZOBZLUDHBTK-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50026730   

TargetSodium-dependent serotonin transporter(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026730(CHEMBL3331503)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human SERT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026730(CHEMBL3331503)
Affinity DataIC50: 45nMAssay Description:Inhibition of human NET expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026730(CHEMBL3331503)
Affinity DataIC50: 330nMAssay Description:Inhibition of human DAT expressed in HEK293 cells at incubated for 15 mins by neurotransmitter reuptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026730(CHEMBL3331503)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human recombinant CYP2C19 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026730(CHEMBL3331503)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant CYP3A4 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026730(CHEMBL3331503)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of human recombinant CYP2D6 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026730(CHEMBL3331503)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by automated whole-cell patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026730(CHEMBL3331503)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human recombinant CYP1A2 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50026730(CHEMBL3331503)
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of human recombinant CYP2C9 incubated for 5 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed