BDBM50026782 5,8-Dimethoxy-1,2,3,4-tetrahydro-isoquinoline::CHEMBL284257

SMILES COc1ccc(OC)c2CNCCc12

InChI Key InChIKey=XYFBJOKZCLYMEM-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50026782   

LigandPNGBDBM50026782(5,8-Dimethoxy-1,2,3,4-tetrahydro-isoquinoline | CH...)
Affinity DataKi:  1.93E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50026782(5,8-Dimethoxy-1,2,3,4-tetrahydro-isoquinoline | CH...)
Affinity DataEC50: >3.00E+4nMAssay Description:Alpha-1 adrenergic receptor agonist activity in rabbit ear arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50026782(5,8-Dimethoxy-1,2,3,4-tetrahydro-isoquinoline | CH...)
Affinity DataKi:  4.98E+4nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed