BDBM50028148 CHEMBL3354004

SMILES COc1ccccc1N[C@@H]1C[C@H](C)N(C(C)=O)c2ccc(cc12)-c1ccc(cc1)C(O)=O

InChI Key InChIKey=LWXZPBREHHJQDV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028148   

TargetBromodomain-containing protein 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50028148(CHEMBL3354004)
Affinity DataIC50: 501nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD3 (1 to 475 aa) (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50028148(CHEMBL3354004)
Affinity DataIC50: 631nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD2 (1 to 473 aa) (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50028148(CHEMBL3354004)
Affinity DataIC50: 631nMAssay Description:Displacement of biotinylated tetra-acetylated histone H4 from His6-tagged BRD4 (1 to 477 aa) (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed