BDBM50028207 CHEMBL3354025

SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=IYBACZJBAZUVGN-UEQSERJNSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50028207   

TargetCeramide glucosyltransferase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028207(CHEMBL3354025)
Affinity DataIC50:  50nMAssay Description:Inhibition of glucosylceramide synthase (unknown origin) assessed as catabolism of NBD-glucosylceramideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028207(CHEMBL3354025)
Affinity DataIC50:  400nMAssay Description:Inhibition of GBA1 (unknown origin) using beta-D-[1-14C]glucocerebroside assessed as 4-methylumbelliferrone by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028207(CHEMBL3354025)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of intestinal maltase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028207(CHEMBL3354025)
Affinity DataIC50:  250nMAssay Description:Inhibition of intestinal sucrase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactase/phlorizin hydrolase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028207(CHEMBL3354025)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of intestinal lactase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50028207(CHEMBL3354025)
Affinity DataIC50:  2nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed