BDBM50028287 6-(4-Methoxy-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline; hydrobromide::CHEMBL538310

SMILES COc1ccc(cc1)C1CN2CCC[C@H]2c2ccccc12

InChI Key InChIKey=QTJOQLPKDFJJFZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028287   

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50028287(6-(4-Methoxy-phenyl)-1,2,3,5,6,10b-hexahydro-pyrro...)
Affinity DataKi:  0.790nMAssay Description:Inhibition of norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50028287(6-(4-Methoxy-phenyl)-1,2,3,5,6,10b-hexahydro-pyrro...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of serotonin (5-HT) uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50028287(6-(4-Methoxy-phenyl)-1,2,3,5,6,10b-hexahydro-pyrro...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of dopamine (DA) uptake into rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed