BDBM50028374 CHEMBL278466::Phosphoric acid mono-[5-(5-chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl] ester::Phosphoric acid mono-[5-(5-chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl] ester(CldUMP)::[5-(5-chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen phosphate(CidUMP)

SMILES C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)Cl)COP(=O)(O)O)O

InChI Key InChIKey=RBQXEHDSKLSKLJ-UHFFFAOYSA-N

Data  2 KI

PDB links: 9 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50028374   

TargetThymidylate synthase(Mouse)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50028374([5-(5-chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-...)
Affinity DataKi:  150nMAssay Description:Time-independent inhibition of thymidylate synthase from FdUrd-resistant L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50028374([5-(5-chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-...)
Affinity DataKi:  300nMAssay Description:Time-independent inhibition of thymidylate synthase from parenteral L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed