BDBM50028855 CHEMBL3342694

SMILES FC(F)(F)c1ccc(NC(=O)c2cccc(NC(=O)c3ccccc3C(F)(F)F)c2)nc1

InChI Key InChIKey=AFXYSMQWYAWGIV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50028855   

TargetProstaglandin E synthase(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50028855(CHEMBL3342694)
Affinity DataIC50: 49nMAssay Description:Inhibition of human mPGES-1 using PGH2 as substrate by RP-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50028855(CHEMBL3342694)
Affinity DataIC50: 500nMAssay Description:Inhibition of mPGES-1 in human A549 cells using arachidonic acid as substrate assessed as inhibition of IL-1beta/TNF-alpha-induced PGE2 production in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed