BDBM50029526 CHEMBL342947::[(S)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenylcarbamoyl}-2-(1H-imidazol-4-yl)-ethyl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)Nc1cccc(c1)C(C1CC1)c1c(O)c2CCCCCCc2oc1=O

InChI Key InChIKey=DSHYGKAKVRNSRB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029526   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029526([(S)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,...)
Affinity DataKi:  3nMAssay Description:Inhibitory activity against HIV-I protease.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50029526([(S)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,...)
Affinity DataIC50: 4.53E+4nMAssay Description:Antiviral activity against HIV-I infected H9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed