BDBM50029547 2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-ylsulfanyl)-benzoylamino]-pentanedioic acid::CHEMBL336487

SMILES CC1=NC2N=C(N)NC(=O)C2C1Sc1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O

InChI Key InChIKey=UWMZMPSPAFBAOA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029547   

TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against thymidylate Synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against thymidylate Synthase from human recombinant sourcesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against dihydro folate reductase from Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against dihydro folate reductase from human recombinant sourcesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against dihydro folate reductase from human recombinant sourcesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed