BDBM50029739 CHEMBL3353414
SMILES CC1Cc2c(c3C(=O)c4ccccc4-c3n2CCc2ccccc2)C(=O)C1
InChI Key InChIKey=ZVASCVRKMXOAJR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50029739
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Claude Bernard University Lyon 1
Curated by ChEMBL
Claude Bernard University Lyon 1
Curated by ChEMBL
Affinity DataKi: 323nMAssay Description:Mixed inhibition of human ABCG2 transfected in human HEK293 cells assessed as Ki1 for inhibition of mitoxantrone efflux measured after 30 mins by FAC...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Claude Bernard University Lyon 1
Curated by ChEMBL
Claude Bernard University Lyon 1
Curated by ChEMBL
Affinity DataKi: 843nMAssay Description:Mixed inhibition of human ABCG2 transfected in human HEK293 cells assessed as Ki2 for inhibition of mitoxantrone efflux measured after 30 mins by FAC...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Claude Bernard University Lyon 1
Curated by ChEMBL
Claude Bernard University Lyon 1
Curated by ChEMBL
Affinity DataIC50: 768nMAssay Description:Inhibition of human ABCG2 transfected in human HEK293 cells assessed as inhibition of mitoxantrone efflux measured after 30 mins by FACS Calibur cyto...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Claude Bernard University Lyon 1
Curated by ChEMBL
Claude Bernard University Lyon 1
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux after 30 mins by FACS methodMore data for this Ligand-Target Pair