BDBM50029776 CHEMBL359455::N-{3-[5-(4-fluorobenzyl)thien-2-yl]prop-2-ynyl}-N-hydroxyurea

SMILES NC(=O)N(O)CC#Cc1ccc(Cc2ccc(F)cc2)s1

InChI Key InChIKey=NITPXQZARBUPNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029776   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50029776(N-{3-[5-(4-fluorobenzyl)thien-2-yl]prop-2-ynyl}-N-...)
Affinity DataIC50: 70nMAssay Description:5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed