BDBM50029932 5,6-Dimethoxy-2-[1-(3-nitro-benzyl)-piperidin-4-ylmethyl]-indan-1-one; hydrochloride::CHEMBL435071::CHEMBL557839

SMILES COc1cc2CC(CC3CCN(Cc4cccc(c4)[N+]([O-])=O)CC3)C(=O)c2cc1OC

InChI Key InChIKey=SQRIUXQNIAMKTL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029932   

TargetAcetylcholinesterase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50029932(CHEMBL557839 | CHEMBL435071 | 5,6-Dimethoxy-2-[1-(...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Acetylcholinesterase activity in mouse brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetAcetylcholinesterase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50029932(CHEMBL557839 | CHEMBL435071 | 5,6-Dimethoxy-2-[1-(...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50029932(CHEMBL557839 | CHEMBL435071 | 5,6-Dimethoxy-2-[1-(...)
Affinity DataIC50: 414nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up to 3 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50029932(CHEMBL557839 | CHEMBL435071 | 5,6-Dimethoxy-2-[1-(...)
Affinity DataIC50: 652nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50029932(CHEMBL557839 | CHEMBL435071 | 5,6-Dimethoxy-2-[1-(...)
Affinity DataIC50: 4.24E+4nMAssay Description:Inhibition of equine serum BuChE using s-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed