BDBM50030333 (3S,6S,7S)-3-(2-Methoxy-phenyl)-7-phenyl-1,8-diaza-spiro[5.5]undecane::CHEMBL332644

SMILES COc1ccccc1[C@@H]1CC[C@@]2(CCCN[C@H]2c2ccccc2)NC1

InChI Key InChIKey=BLYHUYRAYMAUST-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50030333   

TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50030333((3S,6S,7S)-3-(2-Methoxy-phenyl)-7-phenyl-1,8-diaza...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity against substance P (NK-1) receptor in human IM-9 cell using [125I]BH-SPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50030333((3S,6S,7S)-3-(2-Methoxy-phenyl)-7-phenyl-1,8-diaza...)
Affinity DataIC50: 2nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in human IM-9 cells using [125I]Bolton-Hunter SP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed