BDBM50030459 CHEMBL3344321

SMILES [H]/N=C(\N)/NC1CCC(CC1)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)Cc2ccc(c(c2)Cl)Cl

InChI Key InChIKey=OWKCLMWSCHVRNJ-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50030459   

TargetGenome polyprotein(WNV)
Australian National University Canberra

Curated by ChEMBL
LigandPNGBDBM50030459(CHEMBL3344321)
Affinity DataKi:  130nMAssay Description:Inhibition of West Nile virus NS2B (52 to 96 residues)-NS3 (1 to 184 residues) protease using PhAc-Leu-LysLys-Arg-AMC3 TFA as substrate by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
Australian National University Canberra

Curated by ChEMBL
LigandPNGBDBM50030459(CHEMBL3344321)
Affinity DataKi:  130nMAssay Description:Inhibition of West Nile virus NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Australian National University Canberra

Curated by ChEMBL
LigandPNGBDBM50030459(CHEMBL3344321)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of factor Xa (unknown origin) using CH3OCO-dCha-Gly-Arg-pNA as substrate by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetProthrombin(Human)
Australian National University Canberra

Curated by ChEMBL
LigandPNGBDBM50030459(CHEMBL3344321)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of thrombin (unknown origin) using CH3SO2-dCha-Gly-Arg-pNA as substrate by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed