BDBM50030566 6-Bromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dioxolyl]-5,5'-dicarboxylic acid dimethyl ester::CHEMBL317773

SMILES COC(=O)c1cc(OC)c2OCOc2c1-c1c2OCOc2c(OC)c(Br)c1C(=O)OC

InChI Key InChIKey=YDXKUCOMTNYVTF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030566   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030566(6-Bromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dioxolyl...)
Affinity DataIC50: 56nMAssay Description:IC50 value was measured as DNA dependent DNA polymerase associated activity by using 0.05 units of radiolabeled template poly(rA)-oligo(dT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030566(6-Bromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dioxolyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:IC50 value was measured as RNA dependent DNA polymerase associated activity by using 1*10e-3 units of radiolabeled template poly(rC)-oligo(dG)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50030566(6-Bromo-7,7'-dimethoxy-[4,4']bi[benzo[1,3]dioxolyl...)
Affinity DataIC50: 4.50E+3nMAssay Description:IC50 value was measured as RNA dependent DNA polymerase associated activity by using 1*10e-3 units of radiolabeled template poly(rA)-oligo(dT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed