BDBM50030609 3-[(3,5-Bis-trifluoromethyl-benzylamino)-methyl]-2,6,7-trimethyl-4-phenyl-2H-isoquinolin-1-one::CHEMBL104435

SMILES Cc1cc2c(-c3ccccc3)c(CNCc3cc(cc(c3)C(F)(F)F)C(F)(F)F)n(C)c(=O)c2cc1C

InChI Key InChIKey=XTYCUJXOJHSJKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030609   

TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030609(3-[(3,5-Bis-trifluoromethyl-benzylamino)-methyl]-2...)
Affinity DataIC50: 250nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed