BDBM50030611 2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide::CHEMBL107848

SMILES Cc1ccccc1-c1c(C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)n(C)c(=O)c2ccccc12

InChI Key InChIKey=BDFUSNFQDJPSLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030611   

TargetSubstance-P receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030611(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed