BDBM50031281 CHEMBL3357022

SMILES CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3c(CO)ccnc32)CC1

InChI Key InChIKey=BCKYTUFUNAGTDV-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50031281   

TargetHistamine H1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031281BDBM50031281(CHEMBL3357022)
Affinity DataKd:  199nMAssay Description:Binding affinity to human H1 histamine receptor expressed in CHO cells after 1 hr by calcium 5 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetSodium-dependent neutral amino acid transporter B(0)AT2(Human)
Max Planck Institute of Psychiatry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031281BDBM50031281(CHEMBL3357022)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of eGFP-tagged human B0AT2 expressed in HEK293 cells measured within 10 mins by [3H]proline uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed