BDBM50031676 (5S,10S,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,4,5,6,7,8,9,10,11,12,13,14,15-tetradecahydro-cyclopenta[a]phenanthren-3-one::CHEMBL84230

SMILES C[C@]12CCC3C(CC[C@H]4CC(=O)CC[C@]34C)C1CC=C2c1cccnc1

InChI Key InChIKey=FKNZCFYWNHCQGE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031676   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50031676((5S,10S,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,4,...)
Affinity DataIC50: 3nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50031676((5S,10S,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,4,...)
Affinity DataIC50: 4.70nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50031676((5S,10S,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,4,...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed