BDBM50031703 (2S,4S)-2-Amino-4-methyl-pentanedioic acid::2-Amino-4-methyl-pentanedioic acid(S-Me-Glu)::CHEMBL41221

SMILES C[C@@H](C[C@H](N)C(O)=O)C(O)=O

InChI Key InChIKey=KRKRAOXTGDJWNI-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50031703   

TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50031703(2-Amino-4-methyl-pentanedioic acid(S-Me-Glu) | (2S...)
Affinity DataKi:  2.00E+3nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50031703(2-Amino-4-methyl-pentanedioic acid(S-Me-Glu) | (2S...)
Affinity DataKi:  1.00E+4nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetGlutamate receptor 1(Rat)
Symphony Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031703(2-Amino-4-methyl-pentanedioic acid(S-Me-Glu) | (2S...)
Affinity DataIC50: 1.00E+4nMAssay Description:Ability to inhibit [3H]AMPA binding to Ionotropic glutamate receptor AMPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 1(Rat)
Symphony Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031703(2-Amino-4-methyl-pentanedioic acid(S-Me-Glu) | (2S...)
Affinity DataIC50: 1.00E+4nMAssay Description:Ability to inhibit [3H]CGS-19,755 binding to Ionotropic glutamate receptor AMPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50031703(2-Amino-4-methyl-pentanedioic acid(S-Me-Glu) | (2S...)
Affinity DataKi:  4.70E+5nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed