BDBM50031853 ((3E,7E)-4,8,12-Trimethyl-1-phosphono-trideca-3,7,11-trienyl)-phosphonic acid::(2E,6E)-farnesylbisphosphonate::2E,6E-farnesyl bisphosphonate::CHEMBL86513

SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]\[#6]=[#6](/P([#8])([#8])=O)P([#8])([#8])=O

InChI Key InChIKey=QVCZMXTZVIKXJN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031853   

TargetSqualene synthase(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031853(2E,6E-farnesyl bisphosphonate | ((3E,7E)-4,8,12-Tr...)
Affinity DataIC50: 32.4nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50031853(2E,6E-farnesyl bisphosphonate | ((3E,7E)-4,8,12-Tr...)
Affinity DataIC50: 100nMAssay Description:Inhibition of GST-tagged human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50031853(2E,6E-farnesyl bisphosphonate | ((3E,7E)-4,8,12-Tr...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant GGDPS expressed in BL21 gold bacteriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed