BDBM50031867 6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyrido[3,2-d]pyrimidine-2,4-diamine::6-{[Methyl-(3,4,5-trimethoxy-phenyl)-amino]-methyl}-pyrido[3,2-d]pyrimidine-2,4-diamine::CHEMBL52688

SMILES COc1cc(cc(OC)c1OC)N(C)Cc1ccc2nc(N)nc(N)c2n1

InChI Key InChIKey=DQLHWXMDFBDATJ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50031867   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 4.70nMAssay Description:Concentration inhibiting Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 26nMAssay Description:Concentration inhibiting rat liver dihydrofolate reductase. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 44nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute

Curated by ChEMBL
LigandPNGBDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 52nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Baker's yeast)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 130nMAssay Description:Concentration inhibiting Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed