BDBM50032747 CHEMBL3355168

SMILES Cc1ccc(CNC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)cn1

InChI Key InChIKey=OYICHVOOWWQYDE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50032747   

TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032747(CHEMBL3355168)
Affinity DataIC50: 311nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032747(CHEMBL3355168)
Affinity DataIC50: 428nMAssay Description:Inhibition of JNK2 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032747(CHEMBL3355168)
Affinity DataIC50: 905nMAssay Description:Inhibition of JNK3 in human SH-SY5Y cells assessed as reduction in c-Jun phosphorylation by Western blot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032747(CHEMBL3355168)
Affinity DataIC50: 7.79E+3nMAssay Description:Inhibition of JNK1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed