BDBM50032748 CHEMBL3355174

SMILES CC(C)n1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)cn1

InChI Key InChIKey=CUDZNCZDKGCXRX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50032748   

TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032748(CHEMBL3355174)
Affinity DataIC50: 114nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032748(CHEMBL3355174)
Affinity DataIC50: 158nMAssay Description:Inhibition of JNK2 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032748(CHEMBL3355174)
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibition of JNK3 in human SH-SY5Y cells assessed as reduction in c-Jun phosphorylation by Western blot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032748(CHEMBL3355174)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of p38alpha (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50032748(CHEMBL3355174)
Affinity DataIC50: 5.05E+3nMAssay Description:Inhibition of JNK1 (unknown origin) after 1 hr by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed