BDBM50033831 1-[4-(7-Methoxy-3,4-dihydro-naphthalen-1-yl)-butyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL366459

SMILES COc1ccc2CCC=C(CCCCN3CCN(CC3)c3ccccc3OC)c2c1

InChI Key InChIKey=HBJIMGXWEHAIDQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033831   

Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50033831(1-[4-(7-Methoxy-3,4-dihydro-naphthalen-1-yl)-butyl...)
Affinity DataIC50: 1.53nMAssay Description:In vitro binding affinity measured on serotonin 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50033831(1-[4-(7-Methoxy-3,4-dihydro-naphthalen-1-yl)-butyl...)
Affinity DataIC50: 10.6nMAssay Description:In vitro binding affinity measured on dopamine receptor D2 using [3H]spiroperidol as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50033831(1-[4-(7-Methoxy-3,4-dihydro-naphthalen-1-yl)-butyl...)
Affinity DataIC50: 53.5nMAssay Description:In vitro binding affinity measured on sigma opioid receptor using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed