BDBM50033887 CHEMBL3358611

SMILES CC(C)(C)c1cc(CN(C(=O)CN(Cc2ccc(Cl)cc2)S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c2ccc(C(O)=O)c(O)c2)cc(c1)C(C)(C)C

InChI Key InChIKey=AMYVQFXKGYPZLQ-UHFFFAOYSA-N

Data  2 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50033887   

TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033887(CHEMBL3358611)
Affinity DataKi:  146nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033887(CHEMBL3358611)
Affinity DataKi:  1.44E+5nMAssay Description:Inhibition of STAT3 (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033887(CHEMBL3358611)
Affinity DataKd:  287nMAssay Description:Binding affinity to full-length His-tagged STAT3 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033887(CHEMBL3358611)
Affinity DataKd:  42nMAssay Description:Binding affinity to full-length His-tagged STAT5B (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed