BDBM50034028 (S)-9-(3-Dimethylamino-propyl)-4,11-diethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,8,12a-triaza-dibenzo[b,h]fluorene-3,13-dione::CHEMBL275538

SMILES CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2cnc(CCCN(C)C)cc12

InChI Key InChIKey=BTWDAJHCLCCIJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034028   

TargetDNA topoisomerase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50034028((S)-9-(3-Dimethylamino-propyl)-4,11-diethyl-4-hydr...)
Affinity DataIC50: 1.49E+3nMAssay Description:In vitro fragmentation of DNA in the presence of excess calf thymus topoisomerase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed