BDBM50034341 (3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280955

SMILES COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12

InChI Key InChIKey=ZRAGXRIXRXDXCR-DZGCQCFKSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50034341   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  18nMAssay Description:Binding affinity against [3H]-U-86,170-labeled dopamine receptor D2 in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  18nMAssay Description:Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity against cloned mammalian dopamine D2 autoreceptor, expressed in CHO-K1 cells, using [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  25nMAssay Description:Binding affinity against [3H]-raclopride-labeled dopamine receptor D2 in rat striatum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  25nMAssay Description:Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi: >217nMAssay Description:Tested for affinity against cloned mammalian dopamine autoreceptor (DA) D2 receptors expressed in CHO-K1 cells using [3H]spiperone as raidoligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  236nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor from bovine hippocampus, used [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  236nMAssay Description:Tested for affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in homogenized rat brain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  252nMAssay Description:Binding affinity against [3H]-8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  333nMAssay Description:Tested for activity against 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Mus musculus (Mouse))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034341((3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi: >333nMAssay Description:Compound was evaluated for the binding affinity against [3H]-8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed