BDBM50034364 (3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24222

SMILES COc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12

InChI Key InChIKey=ZRAGXRIXRXDXCR-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50034364   

Target5-hydroxytryptamine receptor 1A(Mouse)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034364((3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  3.70nMAssay Description:Compound was evaluated for the binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in cloned CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034364((3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  3.70nMAssay Description:Tested for affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in homogenized rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arris Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034364((3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  16nMAssay Description:Tested for activity against 5-hydroxytryptamine 1A receptor from bovine hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Arris Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034364((3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  16nMAssay Description:Binding affinity against [3H]8-OH-DPAT-labeled 5-hydroxytryptamine 1A receptor sites in bovine hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034364((3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  50nMAssay Description:Compound was evaluated for the binding affinity against [3H]U-86,170-labeled dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034364((3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  50nMAssay Description:In vitro binding affinity against cloned mammalian dopamine D2 autoreceptor, expressed in CHO-K1 cells, using [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034364((3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi:  99nMAssay Description:Binding affinity against [3H]raclopride-labeled dopamine receptor D2 in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50034364((3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydr...)
Affinity DataKi: >217nMAssay Description:Tested for affinity against cloned mammalian dopamine autoreceptor (DA) D2 receptors expressed in CHO-K1 cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed