BDBM50034368 CHEMBL28313::Trifluoro-methanesulfonic acid 7-propylamino-5,6,7,8-tetrahydro-naphthalen-1-yl ester

SMILES CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1

InChI Key InChIKey=ZRWGXXAMGVLDQT-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50034368   

Target5-hydroxytryptamine receptor 1A(Mouse)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034368(Trifluoro-methanesulfonic acid 7-propylamino-5,6,7...)
Affinity DataKi:  2.80nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50034368(Trifluoro-methanesulfonic acid 7-propylamino-5,6,7...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034368(Trifluoro-methanesulfonic acid 7-propylamino-5,6,7...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1D receptor alpha by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034368(Trifluoro-methanesulfonic acid 7-propylamino-5,6,7...)
Affinity DataKi:  108nMAssay Description:In vitro binding affinity towards Dopamine receptor D2 by using [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034368(Trifluoro-methanesulfonic acid 7-propylamino-5,6,7...)
Affinity DataKi:  169nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1D receptor beta by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034368(Trifluoro-methanesulfonic acid 7-propylamino-5,6,7...)
Affinity DataKi: >413nMAssay Description:In vitro binding affinity towards Dopamine receptor D2 by using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50034368(Trifluoro-methanesulfonic acid 7-propylamino-5,6,7...)
Affinity DataKi:  691nMAssay Description:In vitro binding affinity towards Dopamine receptor D3 by using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50034368(Trifluoro-methanesulfonic acid 7-propylamino-5,6,7...)
Affinity DataKi:  1.36E+3nMAssay Description:Binding affinity against dopamine receptor D2 in rat brain tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed