BDBM50034491 4-[5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalen-1-ylamino]-butyric acid::CHEMBL418202

SMILES Cc1noc(NS(=O)(=O)c2cccc3c(NCCCC(O)=O)cccc23)c1C

InChI Key InChIKey=FCVNIXAIYYEZTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034491   

TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034491(4-[5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphtha...)
Affinity DataIC50: 1.96E+3nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed