BDBM50034545 (3-Methyl-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)-p-tolyl-methanol::CHEMBL35209

SMILES Cc1ccc(cc1)C(O)c1nc2CCCCCc2cc1C

InChI Key InChIKey=KLGYQZZTJRHYIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034545   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth Research (U.K.)

Curated by ChEMBL
LigandPNGBDBM50034545((3-Methyl-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyrid...)
Affinity DataIC50: 1.40E+4nMAssay Description:5-lipoxygenase inhibitory activity against rat polymorphonuclear leucocytes from female wistar rat, by using LTB4. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Wyeth Research (U.K.)

Curated by ChEMBL
LigandPNGBDBM50034545((3-Methyl-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyrid...)
Affinity DataIC50: 2.70E+4nMAssay Description:5-lipoxygenase inhibitory activity against rat polymorphonuclear leucocytes from female wistar rat, by using 5-HETE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed