BDBM50034600 (+) 3-[13-methyl-9,13-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3(8),4,6-tetraen-1-yl]phenol::(-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-methyl-2,6-methano-6H-azocino[4,5-b]indole::(-) 3-[13-methyl-9,13-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3(8),4,6-tetraen-1-yl]phenol::1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-methyl-2,6-methano-6H-azocino[4,5-b]indole::3-[13-methyl-9,13-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3(8),4,6-tetraen-1-yl]phenol::CHEMBL290301

SMILES CN1CCC2(CC1Cc1[nH]c3ccccc3c21)c1cccc(O)c1

InChI Key InChIKey=WMJAKEDTFIYKBZ-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50034600   

TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of [3H]- DADLE binding to Rat brain Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of [3H]- DADLE binding to Rat brain Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of [3H]DADLE radioligand binding to rat brain opioid receptor delta 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 21nMAssay Description:Inhibition of [3H]DAMGO radioligand binding to rat brain opioid receptor mu 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 29.8nMAssay Description:Inhibition of [3H]DAMGO radioligand binding to rat brain opioid receptor mu 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]- DAMGO binding to Rat brain Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 347nMAssay Description:Agonistic activity towards Opioid receptor delta 1 as inhibitory activity towards electrically stimulated mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 347nMAssay Description:Opioid activity against delta-receptor of isolated mouse vas deferens(MVD) at 30 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 660nMAssay Description:Inhibition of [3H]DADLE radioligand binding to rat brain opioid receptor delta 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for Inhibition of binding of [3H]- DAMGO at Rat brain mu receptor binding site, Expt-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]U-69593 radioligand binding to Guinea pig opioid receptor kappa 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]- U69,593 binding to Guinea pig Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 1.38E+3nMAssay Description:Opioid activity against delta-receptor of isolated mouse vas deferens(MVD) at 30 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 2.07E+3nMAssay Description:The opioid activity against the mu-receptor in the isolated guinea pig ileum(GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50034600((-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-m...)
Affinity DataIC50: 2.07E+3nMAssay Description:Agonistic activity for Opioid receptor mu 1 as inhibitory activity towards electrically stimulated guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed